Clinical Trial of the Treatment of Bacterial Vaginosis

Grant number: 454644 | Funding period: 2007 - 2010

Completed

Abstract

The objective of this research project is to determine if the treatment of Bacterial Vaginosis (BV) can be improved. Bacterial vaginosis is one of the most common causes of vaginal discharge in women. It can also have serious consequences, such as premature labour and can also increase the risk of HIV transmission. These complication cost communities many millions of dollars; for example in the US it is estimated that premature labour caused by BV alone costs about 1 billion dollars a year. The currently recommended treatment for BV works well initially (first month about 80% respond) but by 12 months most (60%) have relapsed. This randomised clinical study is investigating new ways to treat..

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Related publications (2)

Recurrence of bacterial vaginosis is significantly associated with posttreatment sexual activities and hormonal contraceptive use

CS Bradshaw, LA Vodstrcil, JS Hocking, M Law, M Pirotta, SM Garland, D De Guingand, AN Morton, CK Fairley

2013-03-15

Background. Bacterial vaginosis (BV) recurrence posttreatment is common. Our aim was to determine if behaviors were associated wit..

Efficacy of oral metronidazole with vaginal clindamycin or vaginal probiotic for bacterial vaginosis: Randomised placebo-controlled double-blind trial

CS Bradshaw, M Pirotta, D de Guingand, JS Hocking, AN Morton, SM Garland, G Fehler, A Morrow, S Walker, LA Vodstrcil, CK Fairley

2012-04-03

Background: To determine if oral metronidazole (MTZ-400mg bid) with 2% vaginal clindamycin-cream (Clind) or a Lactobacillus acidop..

University of Melbourne Researchers

Jane Hocking